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Alper Celik

Alper Celik

Turkish Metabolic Surgery Foundation, Turkey

Title: Basic concepts and rationale of metabolic surgery

Biography

Biography: Alper Celik

Abstract

Metabolic Syndrome and two of its most important components, obesity and Type 2 diabetes have reached pandemic\\\\r\\\\nproportions threatening the entire world. Initial treatment options indicating life style changes including diet and exercise\\\\r\\\\nhave failed to achieve desired results for an important proportion of patients and eventually considerable numbers of patients\\\\r\\\\nbecame worse than the pre-treatment status because of reactional weight regain. Currently, the most eff ective treatment for\\\\r\\\\nobesity and Type 2 diabetes is without a doubt, surgical procedures. Th ere is no treatment option that can achieve remission for\\\\r\\\\nthe entire compounds of Metabolic Syndrome with over 90% effi ciency. However, it should be known that there are numerous\\\\r\\\\nmethods used for the surgical treatment of metabolic syndrome and all of these methods have advantages, disadvantages,\\\\r\\\\nrestrictions and effi ciency of their own.\\\\r\\\\nCurrently the most widespread procedures in obesity surgery are gastric bypass and sleeve gastrectomy. Unfortunately\\\\r\\\\nthe third most widespread procedures in terms of frequency are revision operations. Sadly, the word “revision’’ represents\\\\r\\\\nthe disability and ineffi ciency of the operations we perform. Surgical community is focusing on performing tighter sleeves,\\\\r\\\\nnarrower anastomoses, and surgeons are trying to revise failed restrictions with further restriction. As is valid for any restriction\\\\r\\\\ndone on human beings throughout the history with thousands of examples, mechanical restriction and restrictive operations\\\\r\\\\ndone for obese individuals will fail in the end. Anthropometric data also suggests a digestive adaptation based on our feeding\\\\r\\\\nbehavior. Th e success in terms of bariatric and metabolic control relies on the activation of distal intestinal hormones like GLP-\\\\r\\\\n1, Peptide YY and oxyntomodulin which provide an insulin mimetic and anorexiogenic eff ect.\\\\r\\\\nIn the light of all this knowledge and while keeping universal digestive adaptations mechanisms in mind, Metabolic Surgery\\\\r\\\\naims to activate ileum based hormones without causing severe malabsorption. Ileal Transposition and Transit Bipartition\\\\r\\\\nprocedures, two surgical techniques devised with this purpose, will be explained in detail during presentations

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